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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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5-Methyl-7-methoxyisoflavone is an orally active antioxidant with remyelinating activity. It inhibits the enzyme aromatase, interfering with the normal metabolic pathways of testosterone. It is a non-steroidal anabolic isoflavone used as an anabolic agent, showing better potency in increasing muscle mass and endurance. This compound can also be used for fat loss, maintaining low cholesterol levels, and strengthening bones. Additionally, 5-Methyl-7-methoxyisoflavone acts as an inhibitor for NF-κB.
Orally active antioxidant with remyelinating activity.
Inhibits aromatase enzyme.
Non-steroidal anabolic isoflavone, acts as an anabolic agent.
Increases muscle mass and endurance.
Aids in fat loss.
Helps maintain low cholesterol levels.
Strengthens bones.
Inhibitor for NF-κB.
Inhibits the clonogenicity of HCT116 colon cancer cells in vitro.
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PHGDH-inactive is a chemically defined negative control compound used to validate PHGDH inhibitor assays. It is supplied in both ready-to-use solution and solid formats for in vitro research use only.
Used as a negative control in PHGDH inhibitor assays.
Available as a 10 mM solution in DMSO and as solid powders.
High chemical purity (about 99.9%).
Soluble in DMSO at approximately 83.33 mg/mL; ultrasonic assistance may be required.
Store at 4°C protected from light; in solution, store long-term at -80°C.
For research use only; not for human or clinical use.
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Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of the ERalpha signaling pathway.
An isoflavone belonging to the phytoestrogen family.
Potent anti-adipogenic and anti-lipogenic agent.
Attenuates cellular growth.
Promotes apoptotic cell death in breast cancer cells through modulation of the ERalpha signaling pathway.
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An isoflavone glycoside with diverse biological activities; inhibits oleic acid-induced lipid accumulation in HepG2 cells and stimulates glucose uptake in C2C12 mouse skeletal muscle myoblasts at 10 µM; inhibits compound 48/80- or histamine-induced scratching behavior in mice at 2 mg/kg; reduces serum levels of IgE in a mouse model of atopic dermatitis; increases serum levels of osteocalcin and ALP and restores mechanical bone hardness in an ovariectomized rat model of osteoporosis; decreases hepatic cholesterol and triglyceride levels, serum LDL and apolipoprotein B levels, and hepatic injury in a mouse model of fructose-induced liver injury at 80 and 160 mg/kg
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An isoflavonoid with antioxidant activity; scavenges peroxynitrite, nitric oxide radicals, and total ROS (IC50s = 1.36, 1.13, and 6.51 µM, respectively)
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Puerarin (CAS 3681-99-0) is an isoflavone compound isolated from the root of Pueraria lobata It exerts multiple pharmacological effects primarily through modulation of oxidative stress and inflammatory signaling pathways Puerarin has been reported to enhance myocardial perfusion protect against ischemic injury and regulate glucose and lipid metabolism in preclinical models Additionally it demonstrates neuroprotective properties including mitigation of neuronal damage associated with neurodegenerative conditions Puerarin is widely studied for its potential in cardiovascular metabolic and neurological disease research
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